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However, at week 2 zolpidem shortened time to fall asleep greater than trazodone.

Trazodone versus Quetiapine (Seroquel®) The observational study compared and contrasted the efficacy of trazodone and quetiapine (Seroquel), an atypical antipsychotic, for insomnia in persons with with mental illness.

Sometimes people do not read the alcohol warning until they have already taken a medication for a week or two, and they have seen no problems with their glass of wine with dinner.

The sleep promoting effect starts within 1-2 hours and usually lasts about 8 hours.

Benefits Mechanism of action Trazodone is a serotonin reuptake inhibitor and is also a 5-HT2 receptor antagonist.

However, in contrast to the SSRIs, trazodone's antidepressant effects may be due to its antagonistic action at the 5-HT2 receptor site.

Trazodone's hypnotic properties are due to its antihistaminergic effects at the histamine-1 receptor, alpha 1-adrenergic receptor antagonism, and serotonin 5-HT2 receptor antagonism.

Should you only worry about alcohol-drug interactions if you are going to drive?

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